PhD, Associate professor, Research supervisor. Her main research activities focus on investigating the glucose and lipid metabolism in the regulation of the pathogenesis of cancer and metabolic diseases. Special areas of investigation include the molecular mechanism underlying the progression of NAFLD and diabetes, and the lipid metabolic reprogramming in cancer. Her research was supported by the National Natural Science Foundation of China, the Chongqing Research Program of Basic Research and Frontier Technology, the Science and Technology Research Program of Chongqing Municipal Education Commission and the Outstanding Young Scholars of Chongqing Medical University.

Positions:

2017.12-, Associate Professor, Lipid Research Center, Key Laboratory of Molecular Biology of Infectious Diseases, Chongqing Medical University

2013.07-2017.12 Assistant Professor, Lipid Research Center, Key Laboratory of Molecular Biology of Infectious Diseases, Chongqing Medical University

Publications:

1. Luo X, Zheng E, Wei L, Zeng H, Qin H, Zhang X, Liao M, Chen L, Zhao L, Ruan XZ, Yang P*, Chen Y*. The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis.

2. Yang P, Zeng H, Tan W, Luo X, Zheng E, Zhao L, Wei L, Ruan XZ, Chen Y, Chen Y. Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR. FASEB J. 2020 Apr;34(4):5658-5672 (IF=5.391)

3. Yang P, Su C, Luo X, Zeng H, Zhao L, Wei L , Zhang X , Varghese Z , Moorhead JF , Chen Y , Ruan XZ. Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway. Cancer Lett. 2018 Dec 1;438:76-85. (IF=6.491)

4. Yang P, Xiao Y, Luo X, Zhao Y, Zhao L, Wang Y, Wu T, Wei L, Chen Y*. Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice. J Lipid Res, 2017 Jul, 58(7):1417-1427 (IF=4.81)

5. Yang P, Zhao Y, Zhao L, Yuan J, Chen Y, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ. Paradoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo. Sci Rep, 2015 Oct 9, 5:14959 (IF=5.578)