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近5年代表性文章发表情况(2016-2021)

2021

·Li D#, Liu M#, Li Z, Zheng G, Chen A, Zhao L, Yang P, Wei L, Chen Y*, Ruan XZ*. Sterolresistant SCAP overexpression in vascular smooth muscle cells accelerates atherosclerosis by increasing local vascular inflammation through activation of the NLRP3 inflammasome in mice. Aging and disease. 2021 Jun 12 (3) : 747-763

·Luo X#, Zheng E#, Wei L, Zeng H, Qin H, Zhang X, Liao M, Chen L, Zhao L, Ruan XZ, Yang P*, Chen Y*. The fatty acid receptor CD36 promotes HCC progression through activating Src/PI3K/AKT axis-dependent aerobic glycolysis. Cell Death Dis. 2021 Mar 26; 12(4):328.

·Wang M, Xiong H, Chen H, Li Q*, Ruan XZ*. Renal Injury by SARS-CoV-2 Infection: A Systematic Review. Kidney Dis (Basel). 2021; 7(2):100-110.

·Qin H, Chen Y*. Lipid Metabolism and Tumor Antigen Presentation. Adv Exp Med Biol. 2021; 1316: 169-189.

·Zhou C, He Q, Gan H, Zeng T, Liu Q, Moorhead JF, Varghese Z, Ouyang N*, Ruan XZ*. Hyperphosphatemia in chronic kidney disease exacerbates atherosclerosis via a mannosidases-mediated complex-type conversion of SCAP N-glycans. Kidney Int. 2021:S0085-2538(21)00188-5.

·Yu T, Zheng E, Li Y, Li Y, Xia J, Ding Q, Hou Z, Ruan XZ, Zhao L*, Chen Y*. Src-mediated Tyr353 phosphorylation of IP3R1 promotes its stability and causes apoptosis in palmitic acid-treated hepatocytes. Exp Cell Res. 2021; 399(2):112438.

·Lin Z, Gong J, Zhong G, Hu J, Cai D, Zhao L*, Zhao Z *. Identification of Mutator-Derived Alternative Splicing Signatures of Genomic Instability for Improving the Clinical Outcome of Cholangiocarcinoma. Front Oncol. 2021, 14; 11: 666847.

·Zhao L, Li Y, Ding Q, Li Y, Chen Y *, Ruan XZ*. CD36 Senses Dietary Lipids and Regulates Lipids Homeostasis in the Intestine. Front Physiol. 2021, 28; 12: 669279.

·Shi D#; Wu J#; Wu Y; Lin X; Xu C; Lian X*; High-Fat Diet-Related Obesity Promotes Urethane-Induced Lung Tumorigenesis in C57BL/6J Mice, Front Oncol. 2021, 11:620993.


2020

·Luo X#, Li Y#, Yang P, Chen Y, Wei L, Yu T, Xia J, Ruan XZ, Zhao L*,Chen Y*. Obesity Induces Preadipocyte CD36 Expression Promoting Inflammation via the Disruption of Lysosomal Calcium Homeostasis and Lysosome Function. EBioMedicine. 2020 Jun 6; 56: 102797.

·Yang P#, Zeng H#, Tan W, Luo X, Zheng E, Zhao L, Wei L, Ruan XZ*, Chen Y*, Chen Y*. Loss of CD36 impairs hepatic insulin signaling by enhancing the interaction of PTP1B with IR.FASEB J. 2020; 34 (4):5658-5672.


2019

·Li D#, Chen A#, Lan T#, Zou Y, Zhao L, Yang P, Qu H, Wei L, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*.SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up-regulating autophagy in ApoE-/- mice. FASEB J. 2019;33(3):3437-3450

·Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*. CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway. J Lipid Res. 2019; 60(4):844-855.

·Li D#, Chen A#, Lan T#, Zou Y, Zhao L, Yang P, Qu H, Wei L, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*.SCAP knockdown in vascular smooth muscle cells alleviates atherosclerosis plaque formation via up-regulating autophagy in ApoE-/- mice. FASEB J. 2019;33(3):3437-3450

·Li Y, Yang P, Zhao L, Chen Y, Zhang X, Zeng S, Wei L, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*. CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway. J Lipid Res. 2019; 60 (4):844-855.

·Gao J, Lin X, He Y, Fu Y, Wu Y, Liao J, Wu Y*, Lian X*.The Comparison of Different Obesity Indexes and the Risk of Lung Cancer: A Meta-Analysis of Prospective Cohort Studies.Nutr Cancer. 2019; 71(6):908-921.


2018

·Zhao L, Zhang C, Luo X, Wang P, Zhou W, Zhong S, Xie Y, Jiang Y, Yang P, Tang R, Pan Q, Hall AR, Luong TV, Fan J, Varghese Z, Moorhead JF, Pinzani M, Chen Y*, Ruan XZ*.CD36 palmitoylation disrupts free fatty acid metabolism and promotes tissue inflammation in non-alcoholic steatohepatitis. J Hepatol. 2018 ;69(3):705-717

·Yang P#, Su C#, Luo X#, Zeng H, Zhao L, Wei L, Zhang X, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*. Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway. Cancer Lett. 2018; 438: 76-85.

·Ren L, Sun Y, Lu H, Ye D, Han L, Wang N, Daugherty A, Li F, Wang M, Su F, Tao W, Sun J, Zelcer N, Mullick AE, Danser AHJ, Jiang Y, He Y, Ruan X*, Lu X*.(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice From Diet-Induced Obesity and Hepatosteatosis.Circ Res. 2018 Mar 2;122(5):730-741

·Yang P#, Su C#, Luo X#, Zeng H, Zhao L, Wei L, Zhang X, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*. Dietary oleic acid-induced CD36 promotes cervical cancer cell growth and metastasis via up-regulation Src/ERK pathway. Cancer Lett. 2018; 438: 76-85.

·Hamlin A, Chinnarasu S, Ding Y, Xian X, Herz J, Jaeschke A, Hui D. Low density lipoprotein receptor-related protein-1 dysfunction synergizes with dietary cholesterol to accelerate steatohepatitis progression. J Biol Chem. 2018 Jun 22;293(25):9674-9684

·Lin X, Liu L, Fu Y, Gao J, He Y, Wu Y, Lian X*.Dietary Cholesterol Intake and Risk of Lung Cancer: A Meta-Analysis.Nutrients. 2018 Feb 8; 10 (2). pii: E185.


2017

·Zhong S#, Zhao L#, Wang Y, Zhang C, Liu J, Wang P, Zhou W, Yang P, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*. Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes through Histone Deacetylase 2-Dependent Pathway. Antioxid Redox Signal. 2017; 27 (4):201-214.

·Yang X#, Okamura DM#, Lu X, Chen Y, Moorhead J, Varghese Z, Ruan XZ*. CD36 in chronic kidney disease: novel insights and therapeutic opportunities.Nat Rev Nephrol. 2017; 13(12):769-781.

·Yang P, Xiao Y, Luo X, Zhao Y, Zhao L, Wang Y, Wu T, Wei L, Chen Y*. Inflammatory stress promotes the development of obesity-related chronic kidney disease via CD36 in mice. J Lipid Res.2017; 58:(7) 1417-1427.

·Zhong S#, Zhao L#, Wang Y, Zhang C, Liu J, Wang P, Zhou W, Yang P, Varghese Z, Moorhead JF, Chen Y*, Ruan XZ*. Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes through Histone Deacetylase 2-Dependent Pathway. Antioxid Redox Signal. 2017; 27(4):201-214.

·Xian X#*,Ding Y#, Dieckmann M#, Zhou L, Plattner F, Liu M, Parks J, Hammer R, Boucher P, Tsai S,Herz J*. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis. Elife. 2017, 6. pii: e29292

·Lin X, Lu L, Liu L, Wei S, He Y, Chang J, Lian X*. Blood lipids profile and lung cancer risk in a meta-analysis of prospective cohort studies,J Clin Lipidol,2017; 11 (4): 1073~1081

·Chen T,Lu L,Xu C,Lin X,Leung YK,Ho SM,Ruan XZ.,Lian X*. Inhibition Role of Atherogenic Diet on Ethyl Carbamate Induced Lung Tumorigenesis in C57BL/6J Mice,Sci Rep. 2017.7.5,7:4723~4732


2016

·Ding Y#, Huang L#, Xian X#, Yuhanna I, Wasser C, Frotscher M, Mineo C, Shaul P*, Herz J*. Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial adhesion and lesion macrophage accumulation. Sci Signal. 2016; 9(419):ra29.

·Ding Y#,Xian X#*, Holland W,Tsai S,Herz J*.LDL Receptor-Related Protein-1 Protects Against Hepatic Insulin Resistance and hepaticsteatosis. EBioMedicine. 2016, 7:135-145



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